Timothy C. Hain, MD Return to Tumor Index. Page last modified: February 19, 2010
|MRI with gadolinium showing diffuce dural enhancement|
Diffuse Dural Enhancement (DDE) is a finding on MRI scan of the brain. There is a white "high signal" ring around the brain corresponding to the location of the dura.
According to River et al (1996), DDE is often associated with an underlying malignancy . Skull metastases and cranial nerve palsies are associated with malignancy.
Other causes of DDE are related to cerebrospinal fluid (CSF) leak or shunting, with or without symptoms of intracranial hypotension, and to dural sinus thrombosis and meningitis.
With respect to Meningitis, In our clinical practice in Chicago, we recently had a patient present with dural enhancement, in whom their spinal fluid tested positive for West Nile Virus.